Products in development

Theriosol antimicrobial “niosome” based nanotherapeutic as antibiotic replacer


Replace current antibiotic prophylaxis and therapy by natural antimicrobials that does not generate antibiotic resistance in 3 main nosocomial human pathogens: Acinetobacter Baumannii, Staphylococcus aureus, Pseudomonas aeruginosa

Biocidal (G+ & G-) and fungicidal on more than 250 pathogens

no perturbation on microflora in the GI tract of mammals (in vitro test on mices)

  • IV and IP routes under preclinical tests (sepsis murine model with Acinetobacter baumannii)
  • Improved efficiency of “soft niosome” versus lipid micelles or double micellar capsules
  • Development of enteral route with better plasma profile than classical oral route

Artificial insemination

THERIOSOL as antibiotic replacer


We are combining nanotechnology with polypharmacology with a constant focus on synergism at different levels.

We are able to modify the way commercial antibiotics are delivered to pathogens membranes and thus to extent their scope of susceptibility.

We can make Vancomycin (approved for treating gram-positive bacteria) biocidal towards G- bacteria

We have discovered highly potent new spermicides with a new mode of action:

THERIOCIDE is in early pre-development phase for use in mammals

Contact us

Leave us a message and we will get back to you.

© 2022 Totipharmaceutical – Tous droits réservés   •   Conception  Alt’ Informatique